3 between GABA projection neurons and dopamine neurons in the substantia nigra 4 5 6 7 Abbreviated title : Na channels in nigral GABA projection
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چکیده
1 2 Molecular and functional differences in voltage-activated sodium currents 3 between GABA projection neurons and dopamine neurons in the substantia nigra 4 5 6 7 Abbreviated title: Na channels in nigral GABA projection neurons 8 9 Shengyuan Ding, Wei Wei, Fu-Ming Zhou 10 11 Department of Pharmacology, University of Tennessee College of Medicine 12 13 Memphis, TN 38163 14 15 Corresponding author: Fu-Ming Zhou, Department of Pharmacology, University of 16 Tennessee College of Medicine, Memphis, TN 38163 17 Phone: 901-448-1779, Email: [email protected]. 18 19 20 Abstract 255 words 2
منابع مشابه
Molecular and functional differences in voltage-activated sodium currents between GABA projection neurons and dopamine neurons in the substantia nigra.
GABA projection neurons (GABA neurons) in the substantia nigra pars reticulata (SNr) and dopamine projection neurons (DA neurons) in substantia nigra pars compacta (SNc) have strikingly different firing properties. SNc DA neurons fire low-frequency, long-duration spikes, whereas SNr GABA neurons fire high-frequency, short-duration spikes. Since voltage-activated sodium (Na(V)) channels are crit...
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